ModEnzA: Accurate Identification of Metabolic Enzymes Using Function Specific Profile HMMs with Optimised Discrimination Threshold and Modified Emission Probabilities

<table>ROC curves for genome-wide enzyme identification using the ModEnzA profiles. The classification of the complete genomes of the four organisms is shown in (a). A fraction of the EC number profiles (284 out of 2075 Tier I ModEnzA profiles) were retrained with an older version of the ENZYME database and compared to PRIAM and MetaShark (b). ModEnzA-RT-Retrained ModEnzA profiles.</table>

Advances in Bioinformatics

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Figure 2: ModEnzA: Accurate Identification of Metabolic Enzymes Using Function Specific Profile HMMs with Optimised Discrimination Threshold and Modified Emission Probabilities 

Figure 2 | ModEnzA: Accurate Identification of Metabolic Enzymes Using Function Specific Profile HMMs with Optimised Discrimination Threshold and Modified Emission Probabilities 