Research Article

Generation and Analysis of Large-Scale Data-Driven Mycobacterium tuberculosis Functional Networks for Drug Target Identification

Table 1

The number of associations in the MTB functional network, shown separately for each data source and confidence range from low to high.

Association evidence by type Low confidence Medium confidence High confidence

Conserved genomic neighbourhood 1163 6972 4731
Gene fusion events 337 52 99
Phylogenetic Profile 1033 5862 1461
Text mining 1174 722 93
Experimental 220 170 133
Knowledge from database 3 970 2002
Sequence similarity 8524 1345 77
Shared domains 0 20915 17792
Coexpression 6538 225 4

Combined score 6850 32488 25605