Advances in Bioinformatics

Research Article

A Topology-Based Metric for Measuring Term Similarity in the Gene Ontology

Table 6

Some human-mouse protein orthologue pairs without GO-based functional similarity.
Protein IDOrganism Annotation information
GO ID GO name Code Source
BPA1Z1Q3Homo sapiensGO:0042278Purine nucleoside metabolic process IDA UniProtKB
Q3UYG8 Mus musculusGO:0007420 Brain development IEP UniProtKB
Q96EQ8Homo sapiensGO:0032480 Negative regulation of type I interferon production TAS Reactome
GO:0045087 Innate immune response TAS Reactome
Q9D9R0 Mus musculusGO:0016567 Protein ubiquitination EXP GOC
O00451Homo sapiensGO:0007169 Transmembrane receptor protein tyrosine kinase signaling pathway TAS PINC
GO:0035860 Glial cell-derived neurotrophic factor receptor signaling pathway TAS GOC
O08842 Mus musculusGO:0007399 Nervous system development IMP MGI
Q9BS16Homo sapiensGO:0000087 M phase of mitotic cell cycle TAS Reactome
GO:0000236 Mitotic prometaphase TAS Reactome
GO:0000278 Mitotic cell cycle TAS Reactome
GO:0006334 Nucleosome assembly TAS Reactome
GO:0034080 Cenh3-containing nucleosome assembly at centromere TAS Reactome
Q9ESN5 Mus musculusGO:0045944Positive regulation of transcription from RNA polymerase II promoter IDA MGI
O15347 Homo sapiensGO:0006310 DNA recombination ISS UniProtKB
GO:0007275 Multicellular organismal development TAS PINC
O54879 Mus musculusGO:0045578 Negative regulation of B cell differentiation IDA MGI
GO:0045638 Negative regulation of myeloid cell differentiation IDA MGI
Q9NP31 Homo sapiensGO:0001525 Angiogenesis IEA UniProtKB
GO:0007165 Signal transduction TAS PINC
GO:0007275Multicellular organismal development IEA UniProtKB
GO:0030154 Cell differentiation IEA UniProtKB
Q9QXK9 Mus musculusGO:0008283 Cell proliferation IMPoccurs_in (CL:0000084)
Q9C035 Homo sapiensGO:0009615 Response to virus IEA UniProtKB
GO:0044419 Interspecies interaction between organisms IEA UniProtKB
GO:0070206 Protein trimerization IDA UniProtKB:Q9C035-1
P15533 Mus musculusGO:0006351 Transcription, DNA-dependent IEA UniProtKB
GO:0006355 Regulation of transcription, DNA-dependent IEA UniProtKB
MF Q86XR7Homo sapiensGO:0004871 Signal transducer activity IMP UniProtKB
Q8BJQ4 Mus musculusGO:0005515 Protein binding IPI BHF-UCL
Q99218 Homo sapiensGO:0030345 Structural constituent of tooth enamel IDA BHF-UCL
P63277 Mus musculusGO:0005515 Protein binding IPI MGI, BHF-UCL
GO:0008083Growth factor activity IMP BHF-UCL
GO:0042802 Identical protein binding IPI BHF-UCL
GO:0043498 Cell surface binding IMP BHF-UCL
GO:0046848 Hydroxyapatite binding IDA BHF-UCL
P45379 Homo sapiensGO:0003779 Actin binding IDA UniProtKB
GO:0005523 Tropomyosin binding IDA UniProtKB
GO:0030172 Troponin C binding IPI UniProtKB
GO:003113 Troponin I binding IPI UniProtKB
GO:0016887 Atpase activity IDA UniProtKB:P45379-1-6-7-8
P50752 Mus musculus GO:0005200 Structural constituent of cytoskeleton IDAoccurs_in (CL:0000193)
Q9H0E3Homo sapiens GO:0003713 Transcription coactivator activity IDA UniProtKB
GO:0004402 Histone acetyltransferase activity IDA UniProtKB
Q8BIH0 Mus musculus GO:0005515 Protein binding IPI UniProtKB
Q5T9L3 Homo sapiens GO:0004871Signal transducer activity ISS UniProtKB
Q6DID7Mus musculus GO:0005515 Protein binding IPI UniProtKB
GO:0017147 Wnt-protein binding IDA UniProtKB
A8CG34 Homo sapiens GO:0005515 Protein binding IPI UniProtKB
Q8K3Z9 Mus musculus GO:0017056 Structural constituent of nuclear pore IEA ENSEMBL
O15446 Homo sapiens GO:0003899 DNA-directed RNA polymerase activity IEA UniProtKB
Q76KJ5 Mus musculusGO:0005515 Protein binding IPI MGI