Research Article
In Silico Investigation of Flavonoids as Potential Trypanosomal Nucleoside Hydrolase Inhibitors
Figure 3
Structures of chemical compounds used in the study. (a) Chemical structures of AGV and BTB, the cocrystallized ligand of T. b. brucei IAG-NH and IG-NH, respectively. (b) Chemical structures of inosine and guanosine, the natural substrate of both T. b. brucei IAG-NH and IG-NH. (c) Chemical structures of the compounds tested: flavone, 5-hydroxyflavone, 7-hydroxyflavone, apigenin, fisetin, kaempferol, quercetin, and chrysin.
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