Computer Based Correlation of the Texture of P63 Expressed Nuclei with Histological Tumour Grade, in Laryngeal Carcinomas

Table 2

Means, standard deviations, statistical significance, and correlations of features with statistically significant differences between High Grade and Low Grade laryngeal tumor lesions.

	LG-class		HG-class		LG versus HG	LG versus HG
	mv	std	mv	std	Statistical significance	Correlation; at P < 0.05
% P63	84.840	3.251	79.833	9.565	0.02	−0.300
MV^a	5.170	0.260	5.010	0.211	0.03	−0.322
CONT^a	0.216	0.024	0.238	0.02	0.002	0.436
IDF^a	0.893	0.012	0.883	0.009	0.003	−0.434
DVAR^a	0.168	0.014	0.179	0.010	0.003	0.434
DENTR^a	0.515	0.033	0.542	0.023	0.003	0.434
LRE^a	39.475	9.026	32.351	6.122	0.004	−0.428
RLNU^a	0.057	0.008	0.064	0.009	0.009	0.354
RP^a	0.240	0.022	0.261	0.019	0.002	0.447
Solidity	0.945	0.008	0.940	0.005	0.007	−0.332
TamuraH	70.751	7.601	65.974	7.021	0.040	−0.307
EdgeSt	32.205	5.939	28.356	4.245	0.016	−0.356

% P63: percentage of P63 expressed nuclei, MV: mean value, CONT: Contrast, IDF: Inverse Difference Moment, DVAR: Difference Variance, DENTR: Difference Entropy, LRE: Long Runs Emphasis, RLNU: Run Length Nonuniformity, RP: Run Percentage, TamuraH: Tamura histogram feature, EdgeSt: edge statistics feature, mv: mean value, and std: standard deviation, a: average of the feature over four directions (0°, 45°, 90°, and 135°).