Preliminary In Vitro Evaluation of Genistein Chemopreventive Capacity as a Result of Esterification and Cyclodextrin Encapsulation

Figure 1

Chemical esterification of genistein using myristoyl chloride, in chloroform (Clf) media, in the presence of triethylamine (TEA), for 6 hours at reflux temperature. The solvent was removed by evaporation and the products were further purified by column chromatography thus achieving a highly pure genistein ester (GMAE) in 34–39% yield.