Clinical Study

Cytomorphometric Characteristics of Buccal Mucosal Cells in Behçet’s Disease Patients

Table 3

Comparison of the cytomorphometric parameters and the presence of polymorphonuclear leukocytes (PMNL) in Behçet’s disease patients with and without aphthae.

Cytomorphometric parameters
Median (range)
Behçet’s disease patients having aphthae ()Behçet’s disease patients not having aphthae () value

Nuclear area (µm2) 131.1
(13.9–730.2)
188.2
(38.4–1026.7)
<0.001
Cytoplasmic area (µm2) 5709.5
(717.6–27260.4)
7067.5
(2316.9–22819.9)
<0.001
Nucleus/cytoplasm ratio0.02
(0.01–0.06)
0.03
(0.01–0.07)
<0.001
NRF0.9
(0.7–0.9)
0.9
(0.8–0.9)
<0.001
NL (m)15.7
(4.5–143.5)
18.1
(8.8–132.8)
<0.001
NW (m)11.4
(4.3–109.1)
14.2
(5.4–116.8)
<0.001
NP (m)42.7
(13.5–389.4)
50.7
(23.5–378.3)
<0.001
PMNL infiltration
 Present210.548
 Absent1611

Nuclear roundness factor, nuclear length, nuclear width, nuclear perimeter, Pearson chi-squared test, and Mann-Whitney test.