Identification of Malignancy-Associated Changes in Histologically Normal Tumor-Adjacent Epithelium of Patients with HPV-Positive Oropharyngeal Cancer

<div>Regions of interest. (a) Tumor (left) and contralateral normal (right) biopsies were collected at the time of surgery. Three regions of interest corresponding to the tumor (red), adjacent normal epithelium (green), and contralateral normal epithelium (blue) were outlined by the study pathologist and used for analysis. (b) Close-up of each region of interest stained with H&amp;E (left) or Feulgen-thionin (right).</div>

Analytical Cellular Pathology

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Figure 1

Figure 1: Identification of Malignancy-Associated Changes in Histologically Normal Tumor-Adjacent Epithelium of Patients with HPV-Positive Oropharyngeal Cancer 

Figure 1 | Identification of Malignancy-Associated Changes in Histologically Normal Tumor-Adjacent Epithelium of Patients with HPV-Positive Oropharyngeal Cancer 