High PINCH1 Expression in Human Laryngeal Carcinoma Associates with Poor Prognosis
Table 2
Expression of focal adhesion proteins α- and β-parvin in human laryngeal cancer in relation to clinical and pathological parameters.
α-Parvin
value
β-Parvin
value
Low (n, %)
High (n, %)
Low (n, %)
High (n, %)
Age
≤60
12
34.3%
23
65.7%
0.142
16
45.7%
19
54.3%
0.251
>60
7
18.9%
30
81.1%
12
32.4%
25
67.6%
Location
Glottis
11
25.6%
32
74.4%
0.649
15
34.9%
28
65.1%
0.286
Supraglottis
8
29.6%
19
70.4%
13
48.1%
14
51.9%
Subglottis
0
0.0%
2
100.0%
0
0.0%
2
100.0%
Grade
Grade I
2
15.4%
11
84.6%
0.484
5
38.5%
8
61.5%
0.997
Grade II
15
30.6%
34
69.4%
19
38.8%
30
61.2%
Grade III
2
20.0%
8
80.0%
4
40.0%
6
60.0%
N
No
14
26.4%
39
73.6%
0.993
19
35.8%
34
64.2%
0.380
N1–3
5
26.3%
14
73.7%
9
47.4%
10
52.6%
Stage
I
0
0.0%
1
100.0%
0
0.0%
1
100.0%
II
1
25.0%
3
75.0%
3
75.0%
1
25.0%
III
6
24.0%
19
76.0%
0.685
11
44.0%
14
56.0%
0.386
IV
12
28.6%
30
71.4%
14
33.3%
28
66.7%
Statistical analyses were performed by nonparametric tests, and was considered statistically significant. Lymph node (N) metastasis and stage were determined based on TNM, 7th edition [33].