Prognostic Significance of Cyclins A2, B1, D1, and E1 and CCND1 Numerical Aberrations in Oral Squamous Cell Carcinomas

Figure 1

Immunohistochemical staining of cyclins and CCND1 region analysis by fluorescence in situ hybridization technique in OSCC. (a) Low expression for cyclin A2 (magnification ×200). (b) High expression for cyclin A2 (magnification ×200). (c) Low expression for cyclin B1 (magnification ×200). (d) High expression for cyclin B1 (magnification ×200). (e) Low expression for cyclin D1 (magnification ×200). (f) High expression for cyclin D1 (magnification ×200). (g) Low expression for cyclin E1 (magnification ×200). (h) High expression for cyclin E1 (magnification ×200). (i) Low expression for Ki-67 (magnification ×200). (j) High expression for Ki-67 (magnification ×200). (k) Normal CCND1 numerical signals (magnification ×200). (l) Presence CCND1 numerical aberrations (magnification ×200).

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