SGK1 Mediates Hypoxic Pulmonary Hypertension through Promoting Macrophage Infiltration and Activation

<div>SGK1 deficiency decreased proinflammatory cytokine expression in vitro. Expression of MCP-1 (a), IL-1<i>β</i> (b), TNF-<i>α</i> (c), and IL-10 (d) was analyzed by quantitative PCR in bone marrow-derived macrophage stimulated with 50 ng/ml LPS for 4 hours. GAPDH was used to normalize the quantitative real-time data. Results are expressed as relative fold changes compared with the control group. 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Analytical Cellular Pathology

fig6

Figure 6

Figure 6: SGK1 Mediates Hypoxic Pulmonary Hypertension through Promoting Macrophage Infiltration and Activation 