Differential Diagnosis of Autoimmune Encephalitis from Infectious Lymphocytic Encephalitis by Analysing the Lymphocyte Subsets of Cerebrospinal Fluid

Table 2

Comparison of T and B cell proportions in CSF of patients.

	NMDAR-AE	HSVE	TBM
WBC (/μL) [ (range)]	(3-83)^#	(35-220)	(65-278)	28.97	0.011
Lymph (%) [ (range)]	(30-99)	(35-95)	(12-90)	0.245	0.784
CD 3 cell (%) [ (range)]	(1-36)	(2-27)	(2-38)	0.632	0.535
CD4 cell (%) [ (range)]	(3-76)	(12-89)	(11-98)	2.66	0.078
CD8 cell (%) [ (range)]	(32-92)	(21-98)	(8-25)	18.95	0.001
CD4 : CD8 ratios [ (range)]	0.6 : 1 (0.4-1.3)	0.9 : 1 (0.3-1.9)	3.2 : 1 (1.2-5.7)	59.96	0.002
CD20 B cell (%)	(6.5-55)^#	(1-12)	(1-11)	55.84	0.001

Note: WBC (/μL) indicates the mean of the total CSF leukocyte counts; lymph (%) indicates the mean percentage of lymphocytes in the CSF. CD4 3 cell (%), CD4 T cell (%), CD8 T cell (%), and CD20 B cell (%) indicates each mean percentage in the CSF lymphocytes. CD4 : CD8 ratios mean the ratio between the percentages of CD4 and CD8 cells. ^# vs. the HSVE group; vs. the TBM group.