Research Article

N-Acetyl-L-Cysteine Protects Airway Epithelial Cells during Respiratory Syncytial Virus Infection against Mucin Synthesis, Oxidative Stress, and Inflammatory Response and Inhibits HSPA6 Expression

Table 1

There were top 20 differentially expressed genes (|log2 (FC)| >2.5 and adjusted ) between BEAS-2B cells stimulated with UV-inactivated RSV and RSV-infected BEAS-2B cells.

Adj. vallogFCGene symbolFull name

6.24E-08-71.0415.97-7.94HSPA6Heat shock protein family A (Hsp70) member 6
2.64E-07-51.3214.87-4.60ATF3Activating transcription factor 3
4.64E-07-45.7614.37-4.59CXCL8C-X-C motif chemokine ligand 8
5.62E-07-42.6214.04-5.05FOSBFosB proto-oncogene, AP-1 transcription factor subunit
8.14E-07-38.9213.58-4.37NR4A1Nuclear receptor subfamily 4 group A member 1
8.14E-07-38.5713.53-5.46NR4A3Nuclear receptor subfamily 4 group A member 3
1.00E-06-36.3713.21-4.28SIK1Salt inducible kinase 1
1.28E-06-34.5412.92-3.43GEMGTP binding protein overexpressed in skeletal muscle
1.28E-06-34.1812.86-2.91DNAJB1DnaJ heat shock protein family (Hsp40) member B1
1.56E-06-32.9412.64-4.56FOSFos proto-oncogene, AP-1 transcription factor subunit
1.76E-06-32.1912.51-4.16CXCL1C-X-C motif chemokine ligand 1
1.82E-06-31.6312.40-2.92HSPA1BHeat shock protein family A (Hsp70) member 1B
1.82E-06-31.4212.36-3.24NEDD9Neural precursor cell expressed, developmentally downregulated 9
1.89E-06-31.0312.28-2.66MAFFMAF bZIP transcription factor F
2.69E-06-29.4811.97-3.21TNFAIP3TNF alpha-induced protein 3
2.77E-06-29.2011.91-3.56SNAI1Snail family transcriptional repressor 1
3.72E-06-27.5411.53-3.34IL6Interleukin 6
5.85E-06-25.7411.08-4.34NR4A2Nuclear receptor subfamily 4 group A member 2
6.50E-06-25.1810.93-3.62HEY1Hes-related family bHLH transcription factor with YRPW motif 1
7.64E-06-24.4510.73-3.06JUNBJunB proto-oncogene, AP-1 transcription factor subunit