Effects of IFN-B on TRAIL and Decoy Receptor Expression in Different Immune Cell Populations from MS Patients with Distinct Disease Subtypes
Figure 1
Relative quantification of TRAIL mRNA expression in RNA extracted from whole blood, T cells, B cells, and monocytes employing qRT-PCR. (a) In whole blood, TRAIL gene expression was no different between the various groups. (b) In T cells, TRAIL gene expression was also no different among NS and the various patient groups. (c) In B cells, TRAIL gene expression was the same in the various groups examined. (d) In monocytes, TRAIL gene expression was increased in RRQ IFN and SPMS IFN patients relative to NS. TRAIL mRNA was also elevated in RRQ IFN relative to RRQ NO IFN. *,** and ***, Dunn’s post hoc test.
