Review Article

Heterogeneity in Multiple Sclerosis: Scratching the Surface of a Complex Disease

Table 5

Types of cortical lesions described by Bāˆ… et al. 2003 [83].

Typeof cortical lesionExtension

Type IExtension through both white and gray matter
Type IILesion delimited within the cortex. Neither the brain surface nor the subcortical white matter is involved
Type IIIExtended subpial lesions
Type IVExtension throughout the full width of cerebral cortex but white matter is not involved