Review Article
Evaluation of ENA-6 Profile by ELISA Immunoassay in Patients with Systemic Lupus Erythematodes
Table 4
Optimal cut-off, sensitivity, specificity, positive and negative predictive value of ENA6 SM, and CIC in between SLE patients and healthy control.
| | SLE patients versus healthy control | | Marker | Optimal
cut-off | Sensitivity (%) | Specificity (%) | Positive predictive
value (%) | Negative predictive value (%) |
| | Sm/RNP | ≥8,33 EU | 75% | 100% | 100% | 81% | | Jo-1 | ≥1,005 EU | 83% | 90% | 89% | 84% | | SCL-70 | ≥0,385 EU | 96% | 80% | 83% | 96% | | ENA6 Sm | ≥9,56 EU | 70% | 100% | 100% | 76% | | ENA6 SS-A | ≥5,90 EU | 64% | 76% | 72% | 69% | | ENA6 SS-B | ≥5,44 EU | 60% | 73% | 69% | 65% |
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SLE: systemic lupus erythematosus; EU: elisa units.
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