A Comparison of Epitope Repertoires Associated with Myasthenia Gravis in Humans and Nonhuman Hosts
Table 2
(a) Human AChR subunit specificity. (b) Torpedo AChR subunit specificity.
(a)
Subunit
Positive epitopes
Negative peptides
Positive assays
Negative assays
Neg/pos ratio
235
61
746
513
0.69
19
0
29
0
0
12
0
23
1
0.04
35
11
58
82
1.4
37
8
42
50
1.2
(b)
Subunit
Positive epitopes
Negative peptides
Positive assays
Negative assays
Neg/pos ratio
143
32
895
439
0.49
10
0
14
0
0
11
0
28
2
0.07
11
28
20
38
1.9
Listed in the table are the total numbers of epitopes (distinct molecular structure) and then distinct assays captured within the database. By definition this number does not indicate the number of individual epitopes, as each epitope is defined experimentally by one or more assays.
