Heat Shock Proteins: Pathogenic Role in Atherosclerosis and Potential Therapeutic Implications

Table 2

Logistic regression analysis for the impact of various risk factors on high vascular intima-media thickness in a study of 141 young (17- or 18-year old) white males (see [21]).

Risk factor	Odds ratio (95% CI)	𝑃 value
Cigarette smoking	3.58 (1.34–9.54)	0.0108
High-density lipoprotein level	0.56 (0.36–0.89)	0.0144
Alcohol consumption	0.51 (0.30–0.87)	0.0133
Diastolic blood pressure	1.61 (1.03–2.52)	0.0374
Maximum expiratory flow at 50% vital capacity	0.52 (0.33–0.82)	0.0047
HSP60 stimulation index	2.18 (1.32–3.60)	0.0023
HSP60 antibody titer	1.52 (1.00–2.31)	0.0514

Odds ratios were calculated based on a 1 standard deviation unit change in the given variable.