Review Article

Intravenous Immunoglobulin in the Management of Lupus Nephritis

Table 4

Studies included in IVIg therapy for lupus nephritis.

Study Study design

Sherer et al. 2008 [28]62Cohort, 6 courses LD*
Meissner et al. 2000 [37]1Case, 1 course HD
Levy et al. 1999 [46]5Cohort, 1–8 courses HD*
Akashi et al. 1990 [48]2Cohort, 1–3 courses HD
Oliet et al. 1992 [49]1Case, 1 course HD
Winder et al. 1993 [50]2Cohort, 10–20 courses HD
Arahata et al. 1999 [51]1Case RPGN, 1 course HD
Viertel et al. 2000 [52]1Case AKI, 2 courses HD
Gan et al. 2002 [53]4Cohort, 1 course HD
Kamali et al. 2005 [54]4Cohort, 1–6 courses HD
Micheloud et al. 2006 [55]1Case pregnancy, 1 course HD
Levy et al. 2000 [56]7Cohort, 1–6 courses HD
Francioni et al. 1994 [57]12Cohort, 6–24 courses HD
Monova et al. 2002 [58]58Cohort, LD up to 7 years
Bridoux et al. 1998 [59]3Cohort AKI/TMA, 1 course HD
Becker et al. 1995 [60]2ESRD cohort, courses HD
Lin et al. 1989 [61]9Pediatric cohort, 1-2 courses HD
Welch et al. 1995 [62]1Case, 6 courses HD (induction)
Silvestris et al. 1996 [63]3Cohort, 2 courses HD
Boletis et al. 1999 [64]14RCT, 18 courses LD (induction)
Corvetta et al. 1989 [65]3Cohort, courses HD
Zandman-Goddard et al. 2012 [47]11Cohort, 2–17 courses HD
Chacko et al. 2006 [66]1Case, 1 course HD
Tan et al. 2008 [67]1Case, 1 course HD
Ng 1999 [68]1Case, 1 course HD
Ben-Chetrit et al. 1991 [69]1Case, 2 courses HD
Pasatiempo et al. 1994 [70]3Cohort, 1 course
Barron et al. 1992 [71]6Pediatric cohort
CDC MMWR 1999 [72]120Registry, includes non-SLE
Sati et al. 2001 [73]55Cohort, includes non-SLE
Orbach et al. 2004 [74]106Literature review

*Number of patients in study with lupus nephritis receiving IVIg where efficacy or adverse events could be defined based on information provided. LD: low-dose IVIg, HD: high-dose IVIg.