The Role of Simvastatin in the Therapeutic Approach of Rheumatoid Arthritis

Table 3

Adverse events.

Adverse event	Simvastatin group	Control group	𝑃
Elevated aspartate aminotransferase	1 (2%)	2 (4%)	0.558
Elevated alanine aminotransferase	1 (2%)	5 (10%)	0.092
Elevated creatine phosphokinase	1 (2%)	2 (4%)	0.558
Myalgia	2 (4%)	3 (6%)	0.646
Muscle weakness	1 (2%)	2 (4%)	0.558
Abdominal pain	4 (8%)	6 (12%)	0.505
Nausea	6 (12%)	4 (8%)	0.505
Constipation	0 (0%)	1 (2%)	0.315
Diarrhea	0 (0%)	1 (2%)	0.315
Flatulence	1 (2%)	2 (4%)	0.558
Asthenia	2 (4%)	4 (8%)	0.400
Dizziness	1 (2%)	3 (6%)	0.307
Headache	2 (4%)	4 (8%)	0.400
Allergy	0 (0%)	1 (2%)	0.315