Genome-Wide Association Study of Antiphospholipid Antibodies

Table 1

Characteristics of study participants with three antiphospholipid antibodies in the GWAS dataset*.

	ACL		LAC		Anti-𝛽2GPI
	Positive	Negative	Positive	Negative	Positive	Negative
	(𝑛=183)	(𝑛=487)	(𝑛=127)	(𝑛=581)	(𝑛=136)	(𝑛=360)
Mean age ± SD	46.92±11.41	46.19±10.85	45.64±11.35	46.40±11.36	45.91±10.68	46.79±11.18
SLE cases (%)	58.5	58.1	70.8	56.3	71.3	51.9
Controls (%)	41.5	41.9	29.2	43.7	28.7	48.1

∗ACL: anticardiolipin antibodies; LAC: lupus anticoagulant; Anti-𝛽₂GPI: anti-𝛽₂ glycoprotein I antibodies.