Evaluation of SLE Susceptibility Genes in Malaysians

Table 2

Replicated genes and five immune-related pathways. Cells marked with an X represent presence of SNPs associated with SLE in those genes in either cohort. *marks genes present in the pathway.

Gene	B-cell function and signaling	Neutrophil and monocyte function and signaling	NFκB signaling	T-cell function and signaling	TLR and type I IFN signaling
ATG5			*
BANK1	X*
BLK	X*
CD44				X*
ETS1	X*			X*
HLA-DR2	X*			X*
HLA-DR3	X*			X*
ICAMs		X*
IFIH1					X*
IKZF1	X*			X*
IL10	X*	X*		X*
IL21	X*			X*
IRF7					*
IRF8	X*	X*			X*
ITGAM		X*
LYN	X*
NCF2	X*
PHRF1					X*
PRDM1	X*			X*	X*
RASGRP3	X*
SLC15A4			X*
STAT4				X*	X*
TNFAIP3			X*
TNFSF4				X*
TNIP1			X*
TYK2				*
UBE2L3			*
Total	13	4	3	10	5