A Potential Link between Environmental Triggers and Autoimmunity

<table>Superantigens and autoimmunity. Infection can lead to the release of superantigens, which can cross-link between MHCII and TCR, causing broader bystander activation, some of which may be specific for self-antigens, leading to attack on self-tissues.</table>

Autoimmune Diseases

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Figure 8

Figure 8: A Potential Link between Environmental Triggers and Autoimmunity 