Silent Burdens in Disease: Fatigue and Depression in SLE

Table 5

Health-related quality of life.

	Total; 𝑛=148	SLE (1); 𝑛=50	Depression (2); 𝑛=45	Controls (3); 𝑛=53	𝑃	Post hoc analysis
SF-36
Physical functioning^a	71.8 (26.7)	55.8 (30.5)	75.9 (22.2)	84.3 (16.7)	0.000^b	1<2, 3
Role limitations due to physical health problems^a	62.5 (30.8)	44.5 (32.6)	59.8 (23.5)	81.3 (22.4)	0.000^b	1<2<3
Social functioning^a	63.0 (28.6)	61.5 (31.0)	46.6 (22.5)	78.1 (22.5)	0.000^b	2<1<3
Mental health^a	56.8 (22.1)	55.8 (20.2)	43.0 (17.5)	69.3 (20.2)	0.000^b	2<1<3
Role limitations due to emotional problems^a	70.1 (27.9)	68.7 (29.0)	52.4 (22.9)	86.5 (20.5)	0.000^b	2<1<3
Vitality^a	45.6 (22.9)	34.9 (23.1)	39.4 (16.8)	70.0 (18.8)	0.000^b	1, 2<3
Bodily pain^a	60.7 (31.6)	43.7 (34.6)	64.5 (26.1)	73.7 (25.5)	0.000^b	1<2, 3
General health^a	49.8 (23.7)	31.3 (18.5)	56.2 (21.2)	61.9 (19.2)	0.000^b	1<2, 3
PSC^a	0.0 (1.0)	−0.8 (0.9)	0.4 (0.7)	0.5 (0.6)	0.000^b	1<2, 3
MSC^a	0.0 (1.0)	0.1 (0.9)	−0.8 (0.8)	0.6 (0.8)	0.000^b	2<3<1

aMean (standard deviation); ^bANOVA; PSC: physical summary component; MSC: mental summary component.