Research Article

Evaluation of a Multiplex ELISA for Autoantibody Profiling in Patients with Autoimmune Connective Tissue Diseases

Table 5

Results for connective tissue diseases group. Concordance between INNO-LIA and Gennova-PictArray.

INNO-LIA compared with Gennova-PictArray
Kappa (CI)Agree (%)

RNP/Sm0,21 (−0,36–0,77)92
Ro600,22 (0,03–0,42)58
Ro520,63 (0,47–0,79)81
SSB0,71 (0,54–0,88)88
Jo1not defined
Sm Antigen0,22 (−0,38–0,82)93
Scl700,66 (0–1,32)99
CENP-B0,66 (0–1,32)99

Kappa coefficient (0.01–0.2 indicates poor agreement, 0.21–0.4 is fair, 0.41–0.6 is moderate, and 0.61–0.8 is substantial agreement, 0.81–0.99 is almost perfect agreement).