Differential Immunotoxicity Induced by Two Different Windows of Developmental Trichloroethylene Exposure

Table 3

Gene expression in thymi of mice exposed to TCE during gestation.

	Gestation
	Control	TCE 0.01	TCE 0.1
Bax	1.04±0.14	0.78±0.24	1.06±0.75
Bim	1.02±0.15	0.82±0.3	0.87±0.21
Dnmt1	1.0±0.3	1.16±0.5	1.03±0.25
Dnmt3a	1.14±0.56	1.17±0.46	0.93±0.26
Survivin	1.3±0.97	0.53±0.47	0.68±0.42
Aire	1.1±0.58	0.71±0.09	0.76±0.51
Fas	0.96±0.49	0.83±0.46	0.78±0.28
Fasl	1.06±0.42	𝟎.𝟒±𝟎.𝟐𝟓	𝟎.𝟒𝟓±𝟎.𝟐𝟖

Gene expression was examined in thymocytes incubated for 18 hours following isolation from untreated control mice or from mice exposed to TCE during gestation only.
The data represents the mean ± SD. *Significantly different (𝛼<0.05) compared to control values.
The bolded text represents values that are significantly different from control values (𝛼<0.05).