Research Article
Therapeutic Effect of Saponin Rich Fraction of Achyranthes aspera Linn. on Adjuvant-Induced Arthritis in Sprague-Dawley Rats
Table 4
Effect of saponin rich (SR) fraction of Achyranthes aspera on indexes of oxidative stress in liver of arthritic rats.
| Treatment | Dose (mg/kg) | SOD (U/mL/mg of protein) | CAT (U/mL/mg of protein) | GSH (μg/mL/mg of protein) | MDA (nMol/mL/mg of protein) | Nitric oxide (μMol/mL/mg of protein) |
| Control | — | 20.44 ± 0.64 | 179.62 ± 5.42 | 21.96 ± 1.32 | 7.06 ± 0.514 | 11.78 ± 0.91 |
| FCA Control | — | 4.72 ± 0.60# | 88.83 ± 1.83# | 6.99 ± 0.76# | 16.61 ± 0.742# | 90.72 ± 2.86# |
| Indo | 1 | 10.34 ± 0.50 | 122.98 ± 3.51 | 12.83 ± 0.82 | 10.64 ± 0.102 | 32.22 ± 1.66 |
| SR fraction | 50 | 13.37 ± 0.91 | 127.85 ± 2.80 | 15.65 ± 0.95 | 13.71 ± 0.858 | 40.19 ± 1.79 | 100 | 16.75 ± 1.41 | 139.08 ± 2.54 | 15.92 ± 1.21 | 9.22 ± 0.735 | 33.81 ± 2.21 |
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Values are presented as mean ± SEM, . , , and compared with the FCA control group. # compared with vehicle control.
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