Isoniazid Preventive Therapy Adherence and Associated Factors among HIV Positive Patients in Addis Ababa, Ethiopia

Table 2

Factors associated with isoniazid preventive therapy adherence among HIV positive patients in Addis Ababa, 2011.

Variables	Adherence		OR (95% CI)
	Yes	No	Crude	Adjusted
Age
18–27	50	12	1	1
28–37	171	16	2.57 (1.14–5.78)*	2.13 (0.82–5.55)
38–47	82	10	1.97 (0.79–4.89)	1.25 (0.42–3.71)
≥48	38	2	4.56 (0.96–21.60)	3.59 (0.64–20.34)
Sex
Male	108	8	1	1
Female	233	32	0.54 (0.24–1.21)	0.43 (0.16–1.64)
Occupation
Self-employed	149	24	0.59 (0.27–1.28)	0.40 (0.15–1.03)
Employed	88	6	1.46 (0.51–4.17)	0.74 (0.22–2.47)
unemployed	104	10	1	1
ART taking status
Pre-ART	100	18	1	1
On ART	241	22	1.97 (1.01–3.84)*	1.81 (0.82–4.01)
Last dose taken
1–11	220	16	3.79 (1.49–9.64)*	2.12 (0.75–6.05)
12–23	83	12	1.91 (0.71–5.13)	1.39 (0.43–4.47)
≥24	9	4	0.62 (0.15–2.55)	0.26 (0.05–1.38)
Do not remember	29	8	1	1
Duration on IPT
1–2 months	106	15	1	1
3–4 months	126	21	0.85 (0.42–1.73)	0.86 (0.39–1.93)
≥5 months	109	4	3.86 (1.24–12.00)*	5.09 (1.41–18.36)*
Disclosed their IPT taking status
Yes	245	24	1.70 (0.87–3.34)	1.38 (0.63–3.03)
No	96	16	1	1
Information about INH
Yes	337	37	6.83 (1.47–31.70)*	8.50 (0.46–158.25)
No	4	3	1	1
Counseled on adherence
Yes	338	38	5.93 (0.96–36.61)	1.03 (0.03–31.42)
No	3	2	1	1
Made decision to start INH
The patient	102	5	1	1
Family	6	1	0.29 (0.03–2.93)	0.99 (0.07–13.68)
Friends	6	2	0.15 (0.02–0.92)*	0.10 (0.01–0.82)*
Doctors/nurses	227	32	0.35 (0.13–0.92)	0.46 (0.14–1.47)
INH may be dangerous to your health
Strongly agree/agree	85	18	1.02 (0.38–2.62)	1.05 (0.32–3.46)
Strongly disagree/agree	223	15	3.15 (2.00–8.31)*	3.16 (0.95–10.54)
Do not know	33	7	1	1
Chance of getting sick from TB without treatment
High	225	23	1.76 (0.77–4.04)	1.88 (0.70–5.06)
Average/below average	66	8	1.49 (0.54–4.12)	1.12 (0.33–3.77)
Do not know	50	9	1.00	1.00

 *Statistically significant.