Research Article

Estimating Cancer Latency Times Using a Weibull Model

Table 2

Approximate latency times from cancer initiation to diagnosis by cancer site.

Cancer siteSample size5-year survival rateYears from onset to diagnosisMedian age at cancer onset

Acute lymphocytic leukemia 3,701 21.5% 35.7 8.3
Acute monocytic leukemia 1,118 8.8% 15.7 47.3
Acute myeloid leukemia 17,733 12.3% 25.7 39.3
Aleukemic, subleukemic, and NOS 1,785 15.5% 19.3 52.7
Ascending colon 30,038 46.2% 56.8 16.2
Brain 36,828 9.9% 21.9 36.1
Breast 378,477 54.3% 16.3 43.7
Cecum 46,552 36.7% 52.4 20.6
Chronic lymphocytic leukemia 24,466 15.9% 2.2 67.8
Chronic myeloid leukemia 10,498 9.6% 5.1 58.9
Descending colon 13,634 42.4% 52.4 16.6
Esophagus 26,504 6.0% 9.4 56.6
Floor of mouth 5,260 31.5% 21.9 40.1
Gallbladder 8,105 9.6% 25.2 46.8
Gum and other mouth 9,834 37.5% 28.7 34.3
Hypopharynx 5,241 4.8% 9.6 53.4
Kidney and renal pelvis 56,093 33.2% 48.2 14.8
Large intestine, NOS 9,225 19.0% 37.9 36.1
Larynx 22,545 43.1% 35.4 27.6
Liver 22,316 6.0% 10.8 53.2
Lung and bronchus 358,750 6.4% 13.6 53.4
Myeloma 33,252 3.8% 3.6 65.4
NHL-nodal 70,558 27.5% 26.5 37.5
Nasopharynx 4,435 32.4% 25.2 29.8
Nose, nasal cavity, and middle ear 4,062 30.6% 23.0 40.0
Oropharynx 1,763 18.6% 12.3 48.7
Other biliary 8,811 7.4% 16.1 54.9
Other digestive organs 2,145 7.3% 6.6 63.4
Other myeloid/monocytic leukemia 1,424 13.1% 10.5 61.5
Other oral cavity and pharynx 1,722 14.9% 16.9 46.1
Ovary 47,721 25.8% 44.1 17.9
Pancreas 65,835 1.8% 8.4 60.6
Peritoneum, omentum, and mesentery 2,622 11.5% 9.2 56.8
Pleura 5,153 2.5% 4.5 65.5
Rectosigmoid junction 28,603 35.8% 36.6 31.4
Rectum 60,514 34.3% 29.8 37.2
Retroperitoneum 2,433 12.0% 23.1 37.9
Sigmoid colon 69,135 44.3% 52.1 16.9
Small intestine 7,957 25.9% 26.0 38.0
Splenic flexure 7,259 31.7% 42.4 27.6
Stomach 54,521 11.9% 22.3 46.7
Tongue 14,102 33.8% 26.7 33.3
Tonsil 7,429 27.5% 18.9 39.1
Transverse colon 18,325 37.8% 57.0 15.0