Vitamin E and N-Acetylcysteine as Antioxidant Adjuvant Therapy in Children with Acute Lymphoblastic Leukemia

Table 1

Serum glutathione peroxidase (Glu.Px), malondialdehyde (MDA), and tumor necrosis factor-α (TNF-α) in phases I and II of therapy for both leukemia groups.

Groups	Glu.Px (U/L)		MDA (nmol/mL)		TNF-𝛼 (pg/mL)
	After phase I	After phase II	After phase I	After phase II	After phase I	After phase II
Group I
Median	925	1142	3.52	2.79	41.17	40.34
I.Q	846–973	937–1409	2.79–4.14	2.1–3.4	28.5–72.3	13.4–82.3
Group II
Median	949	936	3.57	3.32	39.29	36.25
I.Q.	810–1230	835–1012	2.84–4.23	2.75–4.42	22.1–59.9	18.9–71.8
P	.43	.03	.66	.13	.52	.85

I.Q.: interquartiles (25th–75th). Significance of Mann Whitney U-Wilcoxon Rank test if 𝑃<.05. Phase I: intensive induction chemotherapy. Phase II: CNS intensification phase.