Comorbidities of Idiopathic Thrombocytopenic Purpura: A Population-Based Study

Table 6

Yearly incidence rates ratios between ITP and non-ITP and their 95% confidence interval of 7 comorbidities of priori interest.

(a)

Comorbidity group	Ratio ITP/non-ITP
	[−5 −4[			[−4 −3[			[3 −2[			[−2 −1[			[−1 diag[
Rate ratio	Lower CI	Upper CI	Rate ratio	Lower CI	Upper CI	Rate ratio	Lower CI	Upper CI	Rate ratio	Lower CI	Upper CI	Rate ratio	Lower CI	Upper CI
MI	0.9	0.10	8.10	0.6	0.07	5.0	2.6	0.8	8.1	3.6	1.0	12.5	4.7	1.7	12.6
Breast cancer	1.8	0.2	19.7	0.9	0.1	8.0	0.0	—	—	1.4	0.3	7.3	2.1	0.5	8.9
Chronic renal failure	1.8	0.3	9.8	1.2	0.12	11.5	0.9	0.1	8.0	2.7	0.6	12.1	2.6	0.8	8.1
Viral hepatitis	1.2	0.7	2.2	1.5	0.8	2.6	0.9	0.5	1.5	0.7	0.4	1.4	0.7	0.4	1.25
Liver damage	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—
Systemic lupus	1.8	0.2	19.8	NA	—	—	3.6	0.2	57.4	NA	—	—	Inf	—	—
Thrombo-embolic	1.2	0.1	11.5	0.9	0.1	8.1	1.03	0.21	4.9	7.2	1.3	39.4	1.4	0.4	5.1

(b)

Comorbidity group	Ratio ITP/non-ITP
	[diag +1[			[+1 +2[			[+2 +3[			[+3 +4[			[+4 +5[
Rate ratio	Lower CI	Upper CI	Rate ratio	Lower CI	Upper CI	Rate ratio	Lower CI	Upper CI	Rate ratio	Lower CI	Upper CI	Rate ratio	Lower CI	Upper CI
MI	3.18	0.97	10.4	1.14	0.2	5.5	2.4	0.6	10.1	1.0	0.1	9.3	4.4	0.9	21.6
Breast cancer	0.9	0.1	8.4	0.0	—	—	0.0	—	—	inf	—	—	2.15	0.2	23.7
Chronic renal failure	3.0	0.8	11.3	0.0	—	—	1.9	0.5	7.9	6.2	1.04	37.1	6.5	1.1	39.1
Viral hepatitis	0.6	0.3	1.2	0.8	0.4	1.6	0.7	0.3	1.7	1.2	0.6	2.3	1.3	0.5	3.2
Liver damage	—	—	—	—	—	—	—	—	—	—	—	—	—	—	—
Systemic lupus	Inf	—	—	Inf	—	—	NA	—	—	NA	—	—	Inf	—	—
Thrombo-embolic	1.3	0.3	6.3	1.2	0.3	4.3	0.0	—	—	0.8	0.1	7.1	1.7	0.3	8.9