Comorbidities of Idiopathic Thrombocytopenic Purpura: A Population-Based Study

Table 7

One- and five-year risk of 26-grouped comorbidities and tests over strata after index.

Comorbidities grouped	Test over strata ITP/non-ITP	ITP cohort 𝑛=883				Non-ITP cohort 𝑛=3700
	log-rank^∗	N	Nb comor b	1-year risk	5-year risk	N	Nb comor b	1-year risk	5-year risk
Coronary artery syndrome/myocardial infarction	NS	982	15	0.63%	1.95%	3601	47	0.25%	1.12%
Peripheral vascular diseases	NS	976	22	0.85%	2.86%	3598	60	0.19%	1.45%
Haematological conditions	S	912	90	0.00%	12.59%	3478	149	0.00%	4.37%
Autoimmune	S	1004	13	0.50%	1.39%	3662	14	0.03%	0.28%
Renal	NS	1030	4	0.20%	0.58%	3696	5	0.00%	0.08%
Pulmonary	NS	1022	16	0.42%	1.58%	3678	45	0.11%	1.06%
Oral	S	953	51	2.06%	5.76%	3468	122	0.61%	2.98%
Ophthalmologic	NS	974	32	1.40%	3.81%	3546	97	0.42%	2.88%
Neurological	NS	1021	24	0.80%	2.53%	3682	72	0.27%	1.82%
Neoplasm	S	1026	7	0.51%	0.76%	3685	10	0.00%	0.31%
Musculo-skeletal	S	974	51	2.04%	5.17%	3540	113	0.59%	2.78%
Mood disorder	NS	1021	4	0.10%	0.29%	3661	13	0.05%	0.28%
Infections	S	946	77	2.52%	8.78%	3503	203	1.37%	5.58%
Hypoglycemia	NS	1030	8	0.30%	0.69%	3696	15	0.05%	0.33%
Hypersensitivity	NS	1008	18	0.00%	2.13%	3630	49	0.00%	1.77%
Genitrourinary	S	1000	28	1.03%	3.19%	3597	59	0.31%	1.65%
GastroIntestimnal	NS	907	64	1.96%	8.76%	3324	216	0.81%	5.52%
Edema	NS	970	53	2.58%	5.24%	3508	198	1.08%	5.50%
Diabetes	NS	972	21	0.74%	2.26%	3546	68	0.33%	2.89%
Dermatological conditions	S	788	158	7.19%	20.66%	3107	493	2.67%	13.87%
Cerebrovascular conditions	NS	1015	18	0.62%	2.00%	3661	56	0.30%	1.53%
Constitution	S	916	109	0.00%	14.98%	3425	299	0.00%	9.50%
Congestive heart failure	NS	1010	17	0.81%	1.82%	3636	70	0.52%	2.05%
Breast cancer	NS	1025	3	0.00%	0.30%	3670	15	0.00%	0.44%
Bleeding	S	671	167	9.23%	27.82%	3059	498	2.55%	11.91%
Arrhythmia	NS	1006	14	0.82%	2.32%	3629	81	0.52%	2.32%

^∗NS= Not significant at 5% level; S = Significant at 5% level.