Clinical Study

The Effect of Imatinib Mesylate for Newly Diagnosed Philadelphia Chromosome-Positive, Chronic-Phase Myeloid Leukemia in Sub-Saharan African Patients: The Experience of Côte d'Ivoire

Table 1

Pretreatment characteristics of the study population of 42 patients with CML.

Variableno.

Gender, (%)
 Male26
 Female16
Age (yrs) (median range)40 (16–69)
Time from diagnosis (yr) (median range)1.5 (0.1–7)
ECOG at diagnosis
 0-125 (59)
 2-317 (41)
Hepatomegaly n (%)15 (36)
Splenomegaly, n (%)
 0 cm4 (10)
 1–9 cm bcma25 (59)
 ≥10 cm bcm13 (31)
Peripheral blood (median range)
 Hemoglobin level (g/dL)10.2 (5.7–13.7)
 Platelet count (109/L)331.5 (132–1992)
 Leukocyte count (109/L)211.7 (50–854)
 Basophils in PB (%)0 (0–6)
 Blasts in PB (%)1.9 (1–8)
 Blasts in BM (%)1 (0–4)
Ph status before therapy, n (%)
 Ph1+25 (59)
Additional chromosomal abnormalities17 (41)
Sokal score
 Low risk. (%)11 (16.6)
 Intermediate risk (%)16 (44.5)
 High risk (%)15 (38.9)

Cma: centimeters below the costal margin.