Clinical Study

Current Genetic Epidemiology of 𝛽 -Thalassemias and Structural Hemoglobin Variants in the Lazio Region (Central Italy) Following Recent Migration Movements

Table 2

Interactions between different alleles in the β globin genes (65 immigrant patients).

/ / / Hb variants

Cd 39 homozygous (4)Cd 39 / IVS-I 110 (2)IVS-I 110 homozygous (5)Hb S/Hb S (19)
Cd 39/IVS-I 1 (1)Cd 8/IVS-I 6 (1)IVS-I 110/Hb Knossos (1)Hb S/Hb C (3)
Cd 10/Cd 16 homozygous (1)Cd 41-42/IVS-I 1 (1)IVS-I 110/IVS-II 848 (2)Hb S/Cd 39 (1)
Cd 6 homozygous (1)IVS-I 1/IVS-I 110 (1)IVS-I 110/-87 (1)Hb S/IVS-I 110 (2)
Cd 39/Cd 82-83 (1)Hb Lepore/IVS-I 5 (1)IVS-I 110/Hb E (1)Hb S/Cd 82-83 (1)
Cd 51/Hb Lepore (1)IVS-I 6/-30 (1)Hb C homozygous (3)
Hb E homozygous (5)
Hb E/deletion (1)
IVS-I 6 homozygous (3)
IVS-I 5 homozygous (1)