Iron Loading and Overloading due to Ineffective Erythropoiesis

Table 2

A comparison of erythroid pathologies.

Erythroid condition	Tissue iron overload	Tissue hypoxia	Increased erythropoietin	Increased erythropoiesis
Ineffective erythropoiesis	Yes	Yes	Yes	Yes
Hemolysis	No	Yes	Yes	Yes
Blood loss	No	Yes	Yes	Yes
Iron deficiency anemia	No	Yes	Yes	No
Aplastic anemia	No	Yes	Yes	No
Secondary polycythemia	No	Yes	Yes	Yes
Primary polycythemia	No	No	No	Yes