Case Report
Life-Threatening Adenovirus Infections in the Setting of the Immunocompromised Allogeneic Stem Cell Transplant Patients
Table 1
Patient Demographics. Cy/TBI: Cyclophosphamide/Total Body Irradiation, PBSCT: Peripheral Blood Stem Cell Transplant, MUD: Matched unrelated donor, CML: Chronic Myeloid Leukemia, ALL: Acute Lymphocytic Leukemia, CML: Chronic Myeloid Leukemia, M: male, F: female.
| | Age/Gender | Disease | Pretransplant Therapy | Conditioning Therapy | Type of Transplant | GVHD Prophylaxis | GVHD Onset | Max Grade GVHD |
| 1 | 67/M | Follicular Lymphoma | R/CHOP R/DHAP Fludarabine | Busulfan Fludarabine TBI | Allogeneic PBSCT | MMF Cyclosporine | Day +38 Skin, gut Stage II | III | 2 | 44/M | Follicular Lymphoma | R/CHOP FND-R Rituxan + Bortezomib Genmab Anti-CD20 Ab Study R-ICE salvage | Cy/TBI | Sibling Allogeneic PBSCT | Steroids Methotrexate | Day +20 gut and liver Stage III | IV | 3 | 39/M | CML with T315I mutation | Dasatinib Imatinib 3 + 7 HIDAC 3 + 7 | Cy/TBI | MUD PBSCT | Steroids Methotrexate Cyclosporine | Day +19 Skin, gut, and conjunctivae Stage IV | IV | 4 | 57/F | Follicular Lymphoma | R/CHOP RICE RESHAP RICE | Cy/TBI | Allogeneic PBSCT | Steroids Methotrexate Cyclosporine | Day +30 Gut Stage II | III | 5 | 42/F | ALL | Hyper CVAD | Cy/TBI | MUD | Steroids Methotrexate Cyclosporine | Day +360 Skin, gut Stage IV | IV | 6 | 49/M | Multiple Myeloma | Local Radiation Lenalidomide Bortezomib/Doxil/Dex | Carmustine Etoposide Cytarabine Mephalan | Allogeneic PBSCT | Steroids Methotrexate Cyclosporine | Day +26 gut Stage II | III |
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