Review Article

Flow Cytometric Detection of the Classical Hodgkin Lymphoma: Clinical and Research Applications

Figure 1

Wright-Giemsa-stained cytomorphology of representative, intact flow cytometric cell-sorted HRS cells from lymph nodes involved by CHL with immunophenotypes consistent with CHL. (a) A CHL case flow sorted in absence of blocking antibodies showing the presence of T cell-HRS cell rosettes. (b) The same case as seen in (a) (above) where flow sorted in the presence of blocking antibodies showing only isolated HRS cells, suggesting the blocking antibodies disrupted the rosettes. (c) A CHL case flow sorted in the presence of blocking antibodies. (d) A CHL case flow sorted in the absence of blocking antibodies showing T cell-HRS cell rosettes. (e) A CHL case flow sorted in the absence of blocking antibodies. (© 2006 American Society of Clinical Pathology [9]).
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