Heme Oxygenase-1: A Critical Link between Iron Metabolism, Erythropoiesis, and Development
Figure 1
Heme catabolism initiated by heme oxygenases. Heme oxygenase-1 and 2 (HO-1/2) degrade heme to carbon monoxide (CO), Fe2+, and biliverdin that is then reduced to bilirubin by biliverdin reductase (BVR).
