Review Article

Therapeutic Activity of Lenalidomide in Mantle Cell Lymphoma and Indolent Non-Hodgkin’s Lymphomas

Table 5

Lenalidomide containing regimens in untreated indolent and mantle cell lymphoma.

AuthorYearPhaseHistology Age (range)CombinationORR (%)CR (%)

Fowler et al. [31]2010IIIndolent NHL3056 (36–77)RL8679
Samaniego et al. [32]2011IIIndolent NHL7557 (35–84)RL9066
Tilly et al. [33]2011INHL27NRRL-CHOP9674

ORR: overall response rate; CR: complete response; NR: not reported; RL: rituximab and lenalidomide; RL-CHOP: rituximab, lenalidomide, cyclophosphamide, doxorubicin, vincristine, prednisone.