Research Article
DNMT3A Mutations in Patients with Acute Myeloid Leukemia in South Brazil
Table 4
Description of somatic mutations found in gene DNMT3A.
| Patient identification | Mutation | Allelic change | Exon | Type of mutation | FAB subtype | PCR | Risk group | Karyotype |
| 39 | D748N | G>A | 19 | Missense | M1 | Negative | Intermediate | Normal | 79 | R882H | G>A | 23 | Missense | M1 | Negative | Intermediate | Trisomy (8)(9) | 4 | R882H | G>A | 23 | Missense | M3 | Negative | Intermediate | Normal | 70 | R882H | G>A | 23 | Missense | M2 | Negative | Intermediate | Normal | 41 | H896* | A>G | 23 | Silent | M3 | PML/RARα | Favorable | t(15;17) | 78 | R973Q | G>A | 23 | Missense | — | Negative | — | — |
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