DNMT3A Mutations in Patients with Acute Myeloid Leukemia in South Brazil

Table 4

Description of somatic mutations found in gene DNMT3A.

Patient; identification	Mutation	Allelic change	Exon	Type of; mutation	FAB; subtype	PCR	Risk group	Karyotype
39	D748N	G>A	19	Missense	M1	Negative	Intermediate	Normal
79	R882H	G>A	23	Missense	M1	Negative	Intermediate	Trisomy (8)(9)
4	R882H	G>A	23	Missense	M3	Negative	Intermediate	Normal
70	R882H	G>A	23	Missense	M2	Negative	Intermediate	Normal
41	H896*	A>G	23	Silent	M3	PML/RARα	Favorable	t(15;17)
78	R973Q	G>A	23	Missense	—	Negative	—	—