Research Article
DNMT3A Mutations in Patients with Acute Myeloid Leukemia in South Brazil
Table 5
Clinical characteristics of patients with acute myeloid leukemia with or without DNMT3A mutations.
| Characteristics | Number of pts (%) DNMT3A mutated | Number of pts (%) DNMT3A not mutated | |
| Age (median) | 40.2 | 44.8 | 0.56 | Sex | | | | Male | 50% | 59.3% | 0.68 | Female | 50% | 40.7% | Subtype FAB | | | | M0 | 0% | 7.2% | | M1 | 60% | 18.8% | | M2 | 20% | 30.4% | 0.56 | M3 | 20% | 20.3% | M4 | 0% | 18.8% | | M5 | 0% | 1.4% | | Not M3 | 0% | 2.9% | | Risk groups | | | | Favorable | 20% | 29.8% | | Intermediate | 80% | 59.6% | 1.000 | Unfavorable | 0% | 10.5% | | Leukocytes (×103) (median) | 20.67 | 6.41 | 0.28 | Death | 50% | 51.4% | 1.000 | Relapses | 50% | 30.9% | 0.58 | Refractory | 20% | 19.1% | 0.96 |
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