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Advances in Hematology
Volume 2012 (2012), Article ID 924042, 8 pages
http://dx.doi.org/10.1155/2012/924042
Research Article

Synergistic Effect of Anemia and Red Blood Cells Transfusion on Inflammation and Lung Injury

1Division of Cardiovascular Medicine, The Gill Heart Institute, 741 S. Limestone Street, 252 BBSRB, Lexington, KY 40536-0509, USA
2Medical Service, Lexington VA Medical Center, 1101 Veterans Drive, Lexington, KY 40502, USA

Received 5 March 2012; Accepted 26 June 2012

Academic Editor: Shimon Slavin

Copyright © 2012 Anping Dong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Figure 1: Effect of acute blood loss on plasma levels of inflammatory markers.

Supplementary Figure 2: Effect of volume of blood loss on plasma levels of IL-6 and KC.

Supplementary Figure 3: Effect of volume of blood loss on S1P levels of inflammatory markers.

Supplementary Figure 4: Decline in S1P and dihydroS1P (DHS1P) content of murine RBCs during storage.

Supplementary Figure 5: RBC S1P dynamics in vitro and in vivo.

  1. Supplementary Figures