Eculizumab Therapy Leads to Rapid Resolution of Thrombocytopenia in Atypical Hemolytic Uremic Syndrome

Table 4

Resolution of thrombocytopenia following initiation of eculizumab therapy for aHUS.

	Without concurrent plasma exchange		With concurrent plasma exchange
Source	Steady increase by day 3	Normalized in 7 days	Steady increase by day 3	Normal in 7 days
Literature	10/10	10/12	1/5	0/5
This series	5/5	5/5	0	—
Total	15/15	15/17	1/5*	0/5*

Numerator indicates the number of cases with response; denominator is the number of cases with available data.
and 0.0008, respectively, versus its counter group without plasma exchange (Fisher’s exact test).