Results of a Prospective Study of High-Dose or Conventional Anthracycline-Cyclophosphamide Regimen Plus Radiotherapy for Localized Adult Non-Hodgkin’s Primary Bone Lymphoma

Table 1

Characteristics of 26 adults with non-Hodgkin primary bone lymphoma.

	No.	%
Trial
02	19	73
03	7	27
Gender
Male	16	61
Female	10	39
Stage
I	21	81
II	5	19
B symptoms
No	21	81
Yes	5	19
Site
Axial skeleton	20	59
Spine	13	50
Pelvis	5	19
Rib	2	7
Peripheral skeleton	10	28
Limbs	6	23
Tibia	1	4
Humerus	1	4
Scapula	2	8
Radius/ulna	1	4
Finger	1	4
Skull	4	12
Mandible	3	12
Occipital	1	4
Histology
Diffuse, mixed, small, large	4	15
Diffuse, large cleaved or not	18	69
Large cell immunoblastic	3	12
Anaplastic large-cell ANA Ki+	1	4
Immunophenotyping
B cells	14	54
T cells	1	4
ANA Ki+	1	4
Nonassessable	10	38
LDH > N	7/21	33
PS
0	6	23
1	11	42
2	6	23
3	3	12
IPI score
0	5	19
1	11	42
2	3	11
3	2	7
Non-assessable	5	19

LDH: lactatedehydrogenase; N: normal; PS: performance status; IPI: international prognostic index.
Except for age and bulky disease, the two trials were comparable (no statistical significance). Bulky disease was observed in 9 patients, all included in the trial 02 (𝑃=0.02).
Six patients of the GOELAMS 02 trial had epidural involvement, revealed by paraplegia.