Persistent Polyclonal B Cell Lymphocytosis B Cells Can Be Activated through CD40-CD154 Interaction

Figure 3

Phenotypes of PPBL B cells following low CD154 interaction. CD19, CD27, IgD, and IgM expressions were evaluated by flow cytometry on B cells receiving a low level of CD154 interaction (shown in Figure 2), at days 8 to 9 (9 d) or 13 to 14 (14 d), as indicated. (a) Phenotypic profiles are shown for one control (C-01) and one PPBL sample (8010). (b) The frequencies of cells in the three control samples and the 6 PPBL samples are shown for the main subsets of CD19⁺CD27⁻, CD19⁺CD27⁺, IgM⁻IgD⁻, and IgM⁺IgD⁻ cells, as illustrated in. (a) Data is presented as mean ± SD.

(a)

(b)