Research Article

Persistent Polyclonal B Cell Lymphocytosis B Cells Can Be Activated through CD40-CD154 Interaction

Table 1

Clinical data of PPBL patients.

CharacteristicsPatients
801080118013803080318032

Age (years)504759695649

Lymphocytosis
(×109/L)
6,42,53,92,84,42,4

Lymphocytosis
(% total leukocytosis)
58,432,136,542,556,648,7

B cells/μL5250155091012002240760

Serum IgM
(g/L)
12,17,83,89,69,57,3

Number of BCL-2/Ig
rearrangementsa
3 5 3 7 5 5

HLAA 2, 9
B 14, 44
Dr 2, 5
A 9, 30
B 13, 14
Dr 5, 13
A 9, 39
B 14, 35
Dr 5, 13
A 1, 3
B 7, 57
Dr 7, 14
NDA 11, 29
B 35, 44
Dr 7, 14

Cigarette smokingbYes Stopped × 7 yearsYes Stopped × 3 yearsYes Stopped × 5 years

BCL-2/Ig gene rearrangement was determined as previously described by Delage et al., 2001 [19].
bInformation was reported on day of blood collection.