The key chromosomal translocations in myeloma. A Circos plot, with the chromosomes arranged in a clockwise direction, demonstrating the key translocations in myeloma. The translocations are represented as lines emerging from the immunoglobulin heavy chain (IGH@) locus on chromosome 14 to their respective partner chromosomes. The genes involved in each translocation are represented in boxes outside the plot. All translocations represent primary events except involving MYC which is a secondary translocation.
