Myeloablative Conditioning with PBSC Grafts for T Cell-Replete Haploidentical Donor Transplantation Using Posttransplant Cyclophosphamide

Table 1

Predictors of transplant outcomes following MA haplo HSCT.

	OS		DFS		NRM		Relapse
	HR		HR		HR		HR
DRI (high versus low/int)	13.26	<0.001	10.84	<0.001	15.0	0.004	8.85	0.004
CMI (≥2 versus <2)	3.54	0.010	3.09	0.018	13.6	0.007	—	—
Age (<50 versus ≥50)	1.26	0.038	1.31	0.015	1.43	0.055	—	—

The following variables were considered in Cox analysis: age, diagnosis, Karnofsky performance status (KPS), comorbidity index (CMI), revised Dana-Farber disease risk index (DRI), conditioning regimen (busulfan versus TBI), year of transplant, acute GVHD, and chronic GVHD. Variables were selected by 10% threshold. Acute and chronic GVHD were modeled as time-dependent variables.