Review Article
Noninvasive Biomarkers of Liver Fibrosis: An Overview
Table 4
AUROC for performance of combination algorithms in assessing liver fibrosis.
| | Combination algorithm | Liver disease evaluated by various markers |
AURCO for advanced fibrosis |
AURCO for cirrhosis | References | | CHC | CHB | NAFLD | ALD |
| | SAFE biopsy | 0.89–1 | — | — | — | 0.97–1 | 0.87 | [85, 148, 158] | | Stepwise SAFE algorithm + biopsy | — |
NA | | — | 0.96 | 0.95 | | | Castera | 0.97 | — | — | — | 0.97 | 0.93 | [149] | | Bourliere algorithms | NA | — | — | — | — | — | [153] |
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NA: studied but AUROC is not available.
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